潑尼松

基本信息

中文別名:潑尼松片（溶出檢測用標準片）;17Α,21-二羥基-1,4-孕甾二烯-3,11,20-三酮;去氫腎上腺皮質(zhì)激素;脫氫可的松;強的松;去氫可的松;170,21-二羥基-Δ1,4-孕甾二烯-3,11,20-三酮,17Α,21-DIHYDROXY-1,4-PREGNADIENE-3,11,20-TRIONE;潑尼松,PREDNISONE;去氫皮質(zhì)素
英文別名:1,4-PREGNADIEN-17,21-DIOL-3,11,20-TRIONE; 1,4-PREGNADIEN-17ALPHA,21-DIOL-3,11,20-TRIONE; 1,4-PREGNADIENE-17ALPHA,21-DIOL-3,11,20-TRIONE; 17ALPHA,21-DIHYDROXY-1,4-PREGNADIENE-3,11,20-TRIONE; 17ALPHA,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE; 1-CORTISONE; 1-DEHYDROCORTISONE; (8S,9S,10R,13S,14S,17R)-17-HYDROXY-17-(2-HYDROXY-ACETYL)-10,13-DIMETHYL-7,8,9,10,12,13,14,15,16,17-DECAHYDRO-6H-CYCLOPENTA[A]PHENANTHRENE-3,11-DIONE; DEHYDROCORTISONE; DELTA1-CORTISONE; PREDNISON; PREDNISONUM; 1,2-Dehydrocortisone; 1,4-pregnadiene-16-alpha,21-diol-3,11,20-trione; 11,20-trione,17,21-dihydroxy-pregna-4-diene-3; 11,20-trione,17,21-hydroxy-pregna-4-diene-3; Ancortone; Bicortone; Colisone

物理化學性質(zhì)

熔點 233-235 ºC (DEC.)
比旋光度 169 º (C=0.5, DIOXANE)
折射率 170 ° (C=0.5, Dioxane)
外觀性狀 白色或類白色結晶性粉末，無氣味，味微苦
溶解性 幾乎不溶于水，微溶于乙醇(1：190)和氯仿(1：200)。Mp233-235℃(分解)

潑尼松的作用

【用途一】生化研究；腎上腺皮質(zhì)激素類藥物，具有抗炎、抗過敏等作用。
【用途二】常用于聯(lián)合化療中，可改善病人一般情況，還可用于急性白血病及其他腫瘤等。